Hyposideraemia and Haemolysis in Patients with Lillehei-Kaster or Starr-Edwards Heart Valve Prostheses
| Autor: | Alf Wennevold, Kjeld Lyngborg, Inge H. Rygg, Knud H. Olesen, Jens Damgaard Andersen |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
Male Aortic valve Anemia Hemolytic medicine.medical_specialty Adolescent Iron medicine.medical_treatment Hemolysis Mitral valve Internal medicine Humans Medicine Heart valve Mean corpuscular volume Aged Anemia Hypochromic Hematologic Tests Haptoglobins L-Lactate Dehydrogenase medicine.diagnostic_test biology business.industry Haptoglobin Mitral valve replacement Iron deficiency Middle Aged Haemolysis medicine.disease medicine.anatomical_structure Aortic Valve Heart Valve Prosthesis biology.protein Cardiology Mitral Valve Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Scandinavian Journal of Thoracic and Cardiovascular Surgery. 13:271-275 |
| ISSN: | 0036-5580 |
| DOI: | 10.3109/14017437909100564 |
| Popis: | The haematological status was evaluated in 128 consecutive patients 3 to 24 months after aortic and/or mitral valve replacement with Starr-Edwards' or Lillehei-Kaster prostheses. Anaemia was present in 2%, and hyposideraemia in 20%. The incidence of compensated intravascular haemolysis was very high, subnormal serum haptoglobin being present in 80% of the patients, and serum LDH elevated in 91%. The hyposideraemia was associated with a significant decrease of haemoglobin concentration, haematocrit, mean corpuscular haemoglobin content and mean corpuscular volume, while serum transferrin concentration was elevated. These findings indicate that the hyposideraemia is caused by a true iron deficiency, which can be ascribed to the increased urinary iron loss associated with intravascular haemolysis. The degree of haemolysis appeared to be higher in patients with Starr-Edwards prostheses than in subjects with Lillehei-Raster prostheses, and was more pronounced in patients with double valves than in subjects wit... |
| Databáze: | OpenAIRE |
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