A population-based study on tetanus antitoxin levels in the Netherlands
| Autor: | H.C. Rümke, G. A. M. Berbers, S. van den Hof, H.E. de Melker, Nico J. D. Nagelkerke, M. A. E. Conyn-Van Spaendonck |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Adolescent Population Tetanus Antitoxin complex mixtures Sex Factors Immunity Tetanus Toxoid Humans Medicine Routine vaccination Child education Netherlands education.field_of_study General Veterinary General Immunology and Microbiology business.industry Tetanus Public health Vaccination Age Factors Infant Newborn Public Health Environmental and Occupational Health Infant Tetanus antitoxin Middle Aged medicine.disease Population based study Infectious Diseases Child Preschool Immunology Molecular Medicine Female business |
| Zdroj: | Vaccine. 18:100-108 |
| ISSN: | 0264-410X |
| DOI: | 10.1016/s0264-410x(99)00186-3 |
| Popis: | We assessed the tetanus immunity of the general Dutch population and of religious groups refusing vaccination by means of population-based study to evaluate the effect of tetanus vaccination. More than 95% of those born after the introduction of routine vaccination had tetanus antitoxin levels above the minimum protective level. After the sixth vaccination, a fall in tetanus antitoxin levels occurred. Nevertheless, immunisation in accordance with the routine programme most likely induces protection for much longer than two decades. Not only many members of religious groups who refuse vaccination, but also many adults born before the introduction of vaccination lack tetanus immunity. These cohorts might benefit most from (re)vaccination. |
| Databáze: | OpenAIRE |
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