Cold-stored whole blood platelet function is preserved in injured children with hemorrhagic shock
| Autor: | Barbara A. Gaines, Franklyn P. Cladis, Richard A. Saladino, Darrell J. Triulzi, Mark H. Yazer, Christine M. Leeper |
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| Rok vydání: | 2019 |
| Předmět: |
Blood Platelets
Male Resuscitation Adolescent Shock Hemorrhagic Critical Care and Intensive Care Medicine law.invention 03 medical and health sciences 0302 clinical medicine Refrigeration Interquartile range law Humans Medicine Blood Transfusion Platelet Child Whole blood Platelet Count business.industry 030208 emergency & critical care medicine Length of Stay Intensive care unit Platelet transfusion Blood Preservation Child Preschool Anesthesia Cohort Wounds and Injuries Injury Severity Score Female Surgery business |
| Zdroj: | Journal of Trauma and Acute Care Surgery. 87:49-53 |
| ISSN: | 2163-0763 2163-0755 |
| DOI: | 10.1097/ta.0000000000002340 |
| Popis: | BACKGROUND Recent data demonstrate the safety of uncrossmatched cold-stored whole blood (WB) transfusion in pediatric trauma patients. The hemostatic capabilities of platelets within the cold-stored WB unit have been demonstrated via in vitro studies and animal models. However, platelet function has not been evaluated in pediatric recipients of cold-stored WB transfusions. METHODS Injured children, 2 years or older and 10 kg or greater with hemorrhagic shock received up to 30 mL/kg of cold-stored, low titer ( |
| Databáze: | OpenAIRE |
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