Changes in the enteric vasculature of mice infected with Schistosoma mansoni

Autor:	File Sk, Jerome H. Smith, Nagy Ba
Rok vydání:	1981
Předmět:	Pathology medicine.medical_specialty biology Schistosoma mansoni biology.organism_classification medicine.disease Venous Obstruction Intestines Mice Infectious Diseases Liver Virology medicine Portal hypertension Animals Schistosomiasis Parasitology Mesentery Splanchnic Mesenteries Clearance
Zdroj:	The American journal of tropical medicine and hygiene. 30(5)
ISSN:	0002-9637
Popis:	Mesenteric and intestinal vasculature of mice infected with S. mansoni was injected transaortically with a silicone elastomer. The mesenteries and intestines were then cleared and examined with a stereomicroscope. Marked tortuosity and dilatation of mesenteric and intestinal veins and arteries were found to be confined to areas of oviposition and were associated with small arteriovenous shunts which were not present in control animals or areas of intestine devoid of eggs. These findings suggest that splanchnic arterial-portal venous shunts add a hyperkinetic component to intrahepatic portal venous obstruction and synergistically result in portal hypertension.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d3fdea11f7ae91018f90a0aa686d08 https://pubmed.ncbi.nlm.nih.gov/7283018 Zobrazit plný text záznamu