Comparative cost and clinical effectiveness of clostridial collagenase ointment for chronic dermal ulcers
| Autor: | Adrienne M Gilligan, Marissa J Carter, Curtis Waycaster, Caroline E. Fife, Elizabeth S. Mearns, Catherine T Milne |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Cost effectiveness Cost-Benefit Analysis medicine.medical_treatment Venous leg ulcer Ointments 030207 dermatology & venereal diseases 03 medical and health sciences Wound care 0302 clinical medicine Skin Ulcer medicine Humans 030212 general & internal medicine Wound Healing Debridement integumentary system business.industry Health Policy Skin ulcer medicine.disease Surgery Microbial Collagenase Treatment Outcome Diabetic foot ulcer Microbial collagenase Chronic Disease Quality of Life medicine.symptom Epidemiologic Methods business Wound healing |
| Zdroj: | Journal of Comparative Effectiveness Research. 7:149-165 |
| ISSN: | 2042-6313 2042-6305 |
| DOI: | 10.2217/cer-2017-0066 |
| Popis: | Chronic dermal ulcers affect approximately 2.4–4.5 million people in the USA and are associated with loss of function, decreased quality of life and significant economic burden. Debridement is a critical component of wound care involving removal of nonviable tissue from chronic wounds to stimulate the granulation and epithelialization process. Clostridial collagenase ointment has been used as a method of wound debridement for more than 50 years and is currently the only enzymatic debriding ointment with US FDA approval. This review discusses the results of recent real-world studies that build upon the evidence demonstrating the clinical effectiveness, cost–effectiveness and safety of clostridial collagenase ointment across wound types and care settings. |
| Databáze: | OpenAIRE |
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