Coronary artery calcifications in children with end-stage renal disease

Autor: Ozgur Kasapcopur, Sebuh Kuruoğlu, Huseyin Oflaz, Cengiz Candan, Ibrahim Adaletli, Salim Caliskan, Nil Arisoy, Nur Canpolat, Mahmut Civilibal, Lale Sever
Rok vydání: 2006
Předmět:
Zdroj: Pediatric Nephrology. 21:1426-1433
ISSN: 1432-198X
0931-041X
DOI: 10.1007/s00467-006-0159-6
Popis: Coronary artery calcification (CAC) is common in adults with end-stage renal disease (ESRD), but little is known about the prevalence and the extent of it in children. We used multidetector spiral computed tomography (MDCT), echocardiography, and carotid and brachial high-resolution ultrasonography to screen for the presence and predisposing factors of CAC in 53 children with ESRD [15 hemodialysis (HD) patients, 24 peritoneal dialysis (PD) patients, and 14 renal transplant (rTx) recipients]. CAC was present in 15% of patients (three HD patients, three PD patients, and two rTx). The mean age of the patients with CAC was 16.4 years (range: 11.0–21.2 years), and their median CAC score was 101.3, ranging from 8.5 to 4,322 according to the Agatston method. The patients with CAC had longer duration of total dialysis (P=0.005), had higher time-integrated serum phosphorus (P
Databáze: OpenAIRE