Human parainfluenza virus circulation, United States, 2011–2019

Autor: Susan I. Gerber, Desiree Mustaquim, Rebecca M. Dahl, Amber K. Haynes, John T. Watson, Marie E Killerby, Nicholas P. DeGroote, Calli Taylor
Rok vydání: 2020
Předmět:
Male
0301 basic medicine
Respiratory virus surveillance
Census Region
viruses
Parainfluenza virus
0302 clinical medicine
PIV circulation
Epidemiology
Prevalence
030212 general & internal medicine
Child
Aged
80 and over
virus diseases
respiratory system
Middle Aged
Parainfluenza Virus 2
Human
Parainfluenza Virus 4
Human
Human Parainfluenza Virus
Infectious Diseases
Child
Preschool
Epidemiological Monitoring
Female
Seasons
Adult
medicine.medical_specialty
Adolescent
Demographics
030106 microbiology
Respirovirus Infections
Article
Young Adult
03 medical and health sciences
stomatognathic system
Virology
medicine
Humans
In patient
Enteric virus
Aged
business.industry
Public health
Infant
Rubulavirus Infections
United States
respiratory tract diseases
Parainfluenza Virus 1
Human
Parainfluenza Virus 3
Human
business
Demography
Zdroj: Journal of Clinical Virology
ISSN: 1386-6532
DOI: 10.1016/j.jcv.2020.104261
Popis: Highlights • Human parainfluenza virus type 3 is the most commonly reported parainfluenza virus followed by types 1, 2, and 4, respectively. • Each parainfluenza virus type exhibited a unique circulation pattern. • Parainfluenza type 4 circulated annually and peaked during the winter months. • There was no remarkable distinction in regional versus national seasonal circulation patterns. • The majority of parainfluenza virus detections with available age data occurred among children aged ≤2 years.
Background Human parainfluenza viruses (HPIVs) cause upper and lower respiratory tract illnesses, most frequently among infants and young children, but also in the elderly. While seasonal patterns of HPIV types 1–3 have been described, less is known about national patterns of HPIV-4 circulation. Objectives To describe patterns of HPIVs circulation in the United States (US). Study design We used data from the National Respiratory and Enteric Virus Surveillance System (NREVSS), a voluntary passive laboratory-based surveillance system, to characterize the epidemiology and circulation patterns of HPIVs in the US during 2011–2019. We summarized the number of weekly aggregated HPIV detections nationally and by US census region, and used a subset of data submitted to NREVSS from public health laboratories and several clinical laboratories during 2015–2019 to analyze differences in patient demographics. Results During July 2011 - June 2019, 2,700,135 HPIV tests were reported; 122,852 (5 %) were positive for any HPIV including 22,446 for HPIV-1 (18 %), 17,474 for HPIV-2 (14 %), 67,649 for HPIV-3 (55 %), and 15,283 for HPIV-4 (13 %). HPIV testing increased substantially each year. The majority of detections occurred in children aged ≤ 2 years (36 %) with fluctuations in the distribution of age by type. Conclusions HPIVs were detected year-round during 2011–2019, with type-specific year-to-year variations in circulation patterns. Among HPIV detections where age was known, the majority were aged ≤ 2 years. HPIV-4 exhibited an annual fall-winter seasonality, both nationally and regionally. Continued surveillance is needed to better understand national patterns of HPIV circulation.
Databáze: OpenAIRE
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