N-acetylcysteine in Children with Dengue-associated Liver Failure: A Case Report
| Autor: | Grace Lim, Jan Hau Lee |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Liver transplantation Antiviral Agents Gastroenterology Dengue fever Dengue Acetylcysteine Liver Function Tests Coagulation profile Internal medicine medicine Humans Liver transaminases Child Transaminases Blood coagulation test medicine.diagnostic_test business.industry Liver failure Dengue Virus Liver Failure Acute Prognosis medicine.disease Treatment Outcome Infectious Diseases Immunoglobulin M Immunoglobulin G Pediatrics Perinatology and Child Health Administration Intravenous business Liver function tests medicine.drug |
| Zdroj: | Journal of Tropical Pediatrics. 58:409-413 |
| ISSN: | 1465-3664 0142-6338 |
| Popis: | There is no specific treatment for dengue-associated fulminant liver failure. We report a child with dengue-associated fulminant liver failure who was treated successfully with intravenous N-acetylcysteine. A 6-year-old boy was diagnosed with dengue-associated fulminant liver failure. After administration of intravenous N-acetylcysteine, a rapid decrease in liver transaminases and normalization of coagulation profile was observed followed by clinical improvement and favourable outcome despite factors associated with poor prognosis. The use of intravenous N-acetylcysteine is safe and efficient in the treatment of dengue-associated fulminant liver failure, especially in centres when liver transplantation is not readily available. |
| Databáze: | OpenAIRE |
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