THE EFFECT OF D-Ser (TBU)6-LH-RH-EA10UPON GONADOTROPIN RELEASE IN NORMALLY CYCLIC WOMEN
| Autor: | J. S. E. Dericks-Tan, Hans-Dieter Taubert, E. Hammer |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty medicine.drug_class Endocrinology Diabetes and Metabolism media_common.quotation_subject Clinical Biochemistry Gonadotropin-releasing hormone Biochemistry Gonadotropin-Releasing Hormone Follicle-stimulating hormone Endocrinology Internal medicine medicine Humans Endocrine system Menstrual cycle media_common Dose-Response Relationship Drug Estradiol Chemistry Biochemistry (medical) Serum gonadotropin Luteinizing Hormone Menstruation Female Follicle Stimulating Hormone Gonadotropin Luteinizing hormone Hormone |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 45:597-600 |
| ISSN: | 1945-7197 0021-972X |
| Popis: | D-Ser (TBU)6-LH-RH-EA10 (HOE 766) was found to be approximately 40-times as effective as LH-RH in stimulating LH and FSH release in normally cyclic women. The most pronounced reaction was seen in the late follicular phase, the least one in the early follicular phase. Maximal serum gonadotropin levels were found 4 h after the injection of HOE 766. When 5 microgram was injected every 8 h for 3 days, the initially high release of LH and FSH declined progressively to almost nil. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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