Altered regulator mechanisms of presynaptic adrenergic nerve: A new physiopathological hypothesis in Raynaud's disease
| Autor: | Brotzu Giovanni, Carboni M. Giuseppina, Falchi Susanna, Montisci Roberto |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Regulator Adrenergic Disease Biochemistry Norepinephrine Internal medicine Isoprenaline Receptors Adrenergic beta medicine Humans Aged business.industry Isoproterenol Extremities Raynaud Disease Cell Biology Blood flow Middle Aged Receptors Adrenergic alpha medicine.disease Plethysmography Vasodilation Endocrinology Regional Blood Flow Vasoconstriction Raynaud's disease Female Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Microvascular Research. 27:110-113 |
| ISSN: | 0026-2862 |
| Popis: | The effect of isoprenaline infusion (1 gamma/min) on blood flow in the extremities was studied in 15 Raynaud's disease (RD) patients and 9 healthy controls. A highly significant (P less than 0.0005) decrease in blood flow was seen in the RD subjects. It is suggested that an increased presynaptic beta receptor response to cold and emotional stimulus may be involved in the physiopathogenesis of RD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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