Ultrasound-guided continuous serratus anterior plane block: dexmedetomidine as an adjunctive analgesic with levobupivacaine for post-thoracotomy pain. A prospective randomized controlled study
| Autor: | Dina N Abbas, Ahmed H Bakeer, Rasha B Youssef, Hany Victor Zaki, Nasr M Abdallah |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Sedation medicine.medical_treatment Analgesic serratus anterior plane block Loading dose law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial 030202 anesthesiology law medicine Thoracotomy Dexmedetomidine Journal of Pain Research Original Research business.industry dexmedetomidine thoracic surgery Anesthesiology and Pain Medicine Levobupivacaine Cardiothoracic surgery Anesthesia post-thoracotomy medicine.symptom business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Pain Research |
| ISSN: | 1178-7090 |
| Popis: | Nasr M Abdallah,1 Ahmed H Bakeer,2 Rasha B Youssef,3 Hany V Zaki,4 Dina N Abbas21Department of Anesthesia and Pain Management, Surgical ICU, Faculty of Medicine, Cairo University, Cairo, Egypt; 2Department of Anesthesia and Pain Management, National Cancer Institute, Cairo University, Cairo, Egypt; 3Department of Anesthesia, Surgical ICU and Pain Management, Faculty of Medicine, Helwan University, Cairo, Egypt; 4Department of Anesthesia, Surgical ICU and Pain Management, Faculty of Medicine, Ain Shams University, Cairo, EgyptPurpose: The study aimed to evaluate the analgesic efficiency of dexmedetomidine (DEX) when added to levobupivacaine in continuous ultrasound-guided serratus anterior plane block (SAPB) performed at the end of major thoracic surgery.Methods: This randomized, double-blind trial included 50 adults undergoing thoracic surgery. Continuous SAPB was performed at the end of surgery. Patients were randomized into two groups. Group L (n=25) received levobupivacaine only while Group DL (n=25) received a mixture of levobupivacaine and DEX. All patients received intravenous (IV) paracetamol every 8 hrs. Morphine IV was given according to VAS score of pain as a 5 mg loading dose. The primary outcome measure was postoperative pain intensity. Secondary outcome measures were postoperative morphine consumption and adverse effects.Results: Analgesia was satisfactory in the two groups up to 24 hrs. VAS score was significantly lower in group DL compared to group L between 6 and 24 hrs postoperatively. Total morphine consumption was significantly lower in group DL compared to group L (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|