Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study

Autor:	Rachidi Imorou Sidi, Salifou Kabibou, Dieudonné Gnonlonfoun, Yasmine Hounzangbe-Adoukonou, Dismand Houinato, Mendinatou Agbétou, Colombe Gnansounou, Donald Accrombessi, Thierry Adoukonou, Josiane Angéline Tonato-Bagnan
Přispěvatelé:	Université de Parakou (UP), Neuroépidémiologie Tropicale (NET), Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratory of Chronic and Neurological Diseases Epidemiology (LEMACEN), University of Abomey Calavi (UAC)
Rok vydání:	2020
Předmět:	medicine.medical_specialty Logistic regression lcsh:RC321-571 030218 nuclear medicine & medical imaging 03 medical and health sciences Epilepsy 0302 clinical medicine Obstetrics and gynaecology medicine Childbirth lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Pregnancy Obstetrics business.industry General Neuroscience Case-control study Odds ratio medicine.disease 3. Good health africa epilepsy [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie Original Article Amenorrhea pregnancy prognosis Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery
Zdroj:	Journal of Neurosciences in Rural Practice, Vol 11, Iss 03, Pp 395-402 (2020) Journal of Neurosciences in Rural Practice Journal of Neurosciences in Rural Practice, 2020, 11 (03), pp.395-402. ⟨10.1055/s-0040-1709366⟩
ISSN:	0976-3147
DOI:	10.1055/s-0040-1709366
Popis:	Objective The main purpose of this article is to define prognosis of pregnancies in epileptic women in Benin. Methods This was a case–control study that included 54 epileptic women who had at least one pregnancy matched to 162 controls on age, pregnancy term, and monitoring center. Information about epilepsy, treatment, pregnancy, and childbirth were collected. A logistic regression with odds ratio (OR) calculation was used to study the association. Results During pregnancy 22.22% of epileptic women experienced an increase in seizure frequency. Epileptics had more frequent miscarriages (OR: 1.84 [1.01–3.51]), more incidents during pregnancy (OR: 4.03 [1.04–15.60]), and were more often hospitalized (OR: 3.35 [1.46–7.69]) than women without epilepsy. They, more often, had premature children before 37 weeks of amenorrhea (OR: 2.10 [1.12–3.91]) and gave birth to low-birth-weight children (OR = 2.17 [1.00–4.76]). Conclusion Occurrence of a pregnancy in an epileptic woman in Benin is at risk and requires multidisciplinary monitoring by both neurologist and obstetrician to reduce complications.
Databáze:	OpenAIRE
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