Detection of persistent pestivirus infection in pudú (Pudu puda) in a captive population of artiodactyls in Chile
| Autor: | José Pizarro-Lucero, Ezequiel Hidalgo-Hermoso, Rodrigo Salgado |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
040301 veterinary sciences viruses animal diseases Population Vicugna pacos Virus Virus persistent infection Serology 0403 veterinary science 03 medical and health sciences Neutralization Tests Seroepidemiologic Studies biology.domesticated_animal Pudú Animals Chile education Pathogen Artiodactyla education.field_of_study lcsh:Veterinary medicine General Veterinary biology Reverse Transcriptase Polymerase Chain Reaction Deer Diarrhea Virus 1 Bovine Viral Pestivirus Pestivirus Infections 04 agricultural and veterinary sciences General Medicine Abortion Veterinary biology.organism_classification Virology 030104 developmental biology Zoo Herd lcsh:SF600-1100 Animals Zoo Female Bovine viral diarrhea virus Camelids New World Research Article |
| Zdroj: | BMC Veterinary Research BMC Veterinary Research, Vol 14, Iss 1, Pp 1-7 (2018) |
| ISSN: | 1746-6148 |
| DOI: | 10.1186/s12917-018-1363-x |
| Popis: | Background Bovine Viral Diarrhea Virus (BVDV) is the viral agent causing the most important economic losses in livestock throughout the world. Infection of fetuses before their immunological maturity causes the birth of animals persistently infected with BVDV (PI), which are the main source of infection and maintenance of this pathogen in a herd. There is evidence of susceptibility to infection with BVDV in more than 50 species of the order Artiodactyla, and the ability to establish persistent infection in wild cervid species of South America could represent an important risk in control and eradication programs of BVDV in cattle, and a threat to conservation of these wild species. In this study, a serological and virological study was performed to detect BVDV infection in a captive population of non-bovine artiodactyl species in a Chilean zoo with antecedents of abortions whose pathology suggests an infectious etiology. Results Detection of neutralizing antibodies against BVDV was performed in 112 artiodactyl animals from a zoo in Chile. Three alpacas (Vicugna pacos), one guanaco (Lama guanicoe) and seven pudús (Pudu puda) resulted seropositive, and the only seronegative pudú was suspected to be persistently infected with BVDV. Then two blood samples nine months apart were analyzed by a viral neutralization test and RT-PCR. Non-cytopathogenic BVDVs were isolated in both samples. A phylogenetic analysis showed that the virus was highly related to BVDV-1b strains circulating among Chilean cattle. Conclusions This is the first report of a South American deer persistently infected with Bovine Viral Diarrhea Virus. Further studies are needed to determine the possible role of BVDV as a pathogen in pudús and as a threat to their conservation. |
| Databáze: | OpenAIRE |
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