Convergence of Precision Oncology and Liquid Biopsy in Non-Small Cell Lung Cancer

Autor:	Ebaa Al-Obeidi, Jonathan W. Riess, Umberto Malapelle, Christian Rolfo, David R. Gandara
Přispěvatelé:	Al-Obeidi, Ebaa, Riess, Jonathan W, Malapelle, Umberto, Rolfo, Christian, Gandara, David R
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Tumor mutational burden (TMB) Oncology Liquid biopsy Next-generation sequencing (NGS) Non-small cell lung cancer (NSCLC) Hematology Minimal residual disease (MRD) Circulating tumor DNA (ctDNA)
Popis:	This review article illuminates the role of liquid biopsy in the continuum of care for non-small cell lung cancer (NSCLC). We discuss its current application in advanced-stage NSCLC at the time of diagnosis and at progression. We highlight research showing that concurrent testing of blood and tissue yields faster, more informative, and cheaper answers than the standard stepwise approach. We also describe future applications for liquid biopsy including treatment response monitoring and testing for minimal residual disease. Lastly, we discuss the emerging role of liquid biopsy for screening and early detection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771898ff7126e881ac138cc702cc25c9 https://hdl.handle.net/11588/918507 Zobrazit plný text záznamu