Thyroid vascularity and trapping function: Analysis of very early thyroidal technetium 'uptake'
| Autor: | T. G. H. Rogers, B. E. W. Brownlie, D. I. Armstrong, J. G. Turner |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
medicine.medical_specialty
Pertechnetate Thyroid Gland chemistry.chemical_element Thyroid Function Tests Technetium Thyroid function tests law.invention chemistry.chemical_compound Vascularity law Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Thyroid Neoplasms Radionuclide Imaging Gamma camera medicine.diagnostic_test business.industry Thyroid Thyroid Diseases Function analysis medicine.anatomical_structure Endocrinology chemistry Regional Blood Flow medicine.symptom Pinhole collimator Nuclear medicine business |
| Zdroj: | International Journal of Nuclear Medicine and Biology. 3:65-70 |
| ISSN: | 0047-0740 |
| DOI: | 10.1016/0047-0740(76)90019-x |
| Popis: | A method is presented for analysing flow curves recorded over the neck during the first three minutes following the injection of 99 m Tc-pertechnetate, using a gamma camera fitted with a pinhole collimator interfaced to a minicomputer. The analysis involves the identification of two distinct components in the flow curve, namely “thyroid vascularity” (derived from the height of the initial rise in the curve) and “uptake slope,” which is a sensitive measure of true thyroidal pertechnetate trapping function. Clinical results on 157 patients revealed that whereas the uptake slope correlates well with 10-min uptake and other established thyroid function tests, the gland vascularity correlates rather poorly. Consequently, it is shown that in certain types of thyroid physiology misleading results can be obtained from conventional “early uptake” measurements, when a high vascularity occurs together with a low uptake slope, or vice versa. Amongst possible further applications of this method, it should be particularly valuable in elucidating the effect of long term antithyroid drugs upon thyroid physiology. |
| Databáze: | OpenAIRE |
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