Effect of synthetic chicken vasoactive intestinal peptide on pancreatic blood flow and on exocrine and endocrine secretions of the pancreas in dogs
| Autor: | Masaharu Takeyama, Tamotsu Kawano, Haruaki Yajima, Kazutomo Inoue, Teruji Kim, Takayoshi Tobe, Takashi Suzuki, Koichi Shima |
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| Rok vydání: | 1983 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty animal structures Physiology medicine.medical_treatment Vasoactive intestinal peptide Blood Pressure Gastrointestinal Hormones Dogs Pancreatic Juice Internal medicine medicine Animals Bile Insulin Endocrine system Secretion Pancreas business.industry Gastroenterology Hepatology Hormones Bicarbonates medicine.anatomical_structure Endocrinology Blood pressure Regional Blood Flow Pancreatic juice Female business Chickens hormones hormone substitutes and hormone antagonists Vasoactive Intestinal Peptide |
| Zdroj: | Digestive Diseases and Sciences. 28:724-732 |
| ISSN: | 1573-2568 0163-2116 |
| DOI: | 10.1007/bf01312563 |
| Popis: | This study was undertaken to determine the effect of synthetic chicken vasoactive intestinal peptide (VIP) on pancreatic blood flow, exocrine and endocrine secretions of the pancreas, and biliary secretion in dogs. The effect of synthetic chicken VIP on pancreatic blood flow and systemic arterial pressure was identical to that of natural chicken VIP in dogs. The present study demonstrated that synthetic chicken VIP induces significant increases in pancreatic blood flow, pancreaticobiliary secretion, and blood levels of insulin and glucose in dogs. Both the volume of pancreatic juice and blood levels of insulin were increased in consonance with the increase of pancreatic blood flow. This study suggests that the stimulatory effects of synthetic chicken VIP on exocrine and endocrine secretions of the pancreas may be related to the increased pancreatic blood flow elicited by synthetic chicken VIP. |
| Databáze: | OpenAIRE |
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