Computer simulation of arterial flow with applications to arterial and aortic stenoses
| Autor: | Donald F. Young, Thomas R. Rogge, N. Stergiopulos |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
medicine.medical_specialty
Materials science Biomedical Engineering Biophysics Hemodynamics Arterial Occlusive Diseases Blood Pressure Constriction Pathologic Normal flow Constriction Internal medicine medicine Humans Computer Simulation Orthopedics and Sports Medicine Cardiac Output Rehabilitation Models Cardiovascular Aortic Valve Stenosis Arteries Pulse pressure Peripheral Femoral Artery medicine.anatomical_structure Flow (mathematics) Regional Blood Flow Arterial flow Pulsatile Flow Blood Circulation Cardiology Vascular Resistance Radiology Rheology Artery |
| Zdroj: | Journal of Biomechanics. 25:1477-1488 |
| ISSN: | 0021-9290 |
| DOI: | 10.1016/0021-9290(92)90060-e |
| Popis: | A computer model for simulating pressure and flow propagation in the human arterial system is developed. The model is based on the one-dimensional flow equations and includes nonlinearities arising from geometry and material properties. Fifty-five arterial segments, representing the various major arteries, are combined to form the model of the arterial system. Particular attention is paid to the development of peripheral pressure and flow pulses under normal flow conditions and under conditions of arterial and aortic stenoses. Results show that the presence of severe arterial stenoses significantly affects the nature of the distal pressure and flow pulses. Aortic stenoses also have a profound effect on central and peripheral pressure pulse formation. Comparison with the published experimental data suggests that the model is capable of simulating arterial flow under normal flow conditions as well as conditions of stenotic obstructions in a satisfactory manner. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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