The prevalence of monosodium urate and calcium pyrophosphate crystals in synovial fluid from wrist and finger joints
| Autor: | Augusta Ortolan, Francesca Oliviero, Roberta Ramonda, Leonardo Punzi, Paola Frallonardo, Ariela Hoxha, Mariagrazia Lorenzin, Paola Galozzi, Marta Favero, Anna Scanu |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Wrist Joint 0301 basic medicine Arthritis Comorbidity Osteoarthritis Calcium Pyrophosphate Gastroenterology chemistry.chemical_compound 0302 clinical medicine Immunology and Allergy Aged 80 and over Calcium pyrophosphate Middle Aged Rheumatoid arthritis Female Hand diseases Monosodium urate crystals Pyrophosphate crystals Synovial fluid Rheumatology Immunology Joint Diseases Crystallization Adult musculoskeletal diseases medicine.medical_specialty 03 medical and health sciences Psoriatic arthritis Predictive Value of Tests Finger Joint Rheumatic Diseases Internal medicine medicine Humans Aged Retrospective Studies 030203 arthritis & rheumatology business.industry medicine.disease Uric Acid Surgery Gout body regions 030104 developmental biology chemistry business |
| Zdroj: | Rheumatology International. 36:443-446 |
| ISSN: | 1437-160X 0172-8172 |
| DOI: | 10.1007/s00296-015-3376-0 |
| Popis: | The aim of this study was to assess the frequency of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluids (SFs) aspirated from wrist and finger joints of patients with previously diagnosed joint diseases. We reviewed the results of SF analysis of 1593 samples and identified 126 patients with effusions in the small joints of the hands and wrists. We reported from patients' medical files data about sex, age, diagnosis, disease duration and the microscopic SF results. The prevalence of CPP crystals in SF was 85.71% in CPP-crystals arthritis (CPP-CA), 19.35% in rheumatoid arthritis (RA), 13.89% in osteoarthritis (OA) and 0% in psoriatic arthritis (PsA), spondyloarthritis (SpA), gout and miscellanea. The prevalence of MSU crystals in SF was 83.3% in gout, 10% in PsA, 2.8% in OA and 0% in RA, SpA, miscellanea and CPP-CA. Consistent with previously reported data concerning the big joints, microcrystals can be frequently found also in the small joints of patients with previous diagnosis. The finding underlines the importance of analyzing SF from the hand and wrist joints in the attempt to identify comorbidities associated with the presence of crystals and to develop targeted treatment strategies. |
| Databáze: | OpenAIRE |
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