Avelumab plus axitinib therapy for renal cell carcinoma in a patient with pulmonary alveolar proteinosis: A case report
| Autor: | Yusuke Tsuji, Youtarou Takaku, Nobuaki Shimizu, Masaru Hasumi, Kazumichi Muramatsu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Avelumab Axitinib business.industry Urology Nodule (medicine) medicine.disease Diseases of the genitourinary system. Urology Renal cell carcinoma Oncology medicine Effective treatment In patient RC870-923 Radiology Pulmonary alveolar proteinosis medicine.symptom business medicine.drug Rare disease |
| Zdroj: | Urology Case Reports Urology Case Reports, Vol 39, Iss, Pp 101843-(2021) |
| ISSN: | 2214-4420 |
| Popis: | Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the abnormal accumulation of surfactant-derived substances in the lungs. To the best of our knowledge, the successful treatment of metastatic renal cell carcinoma in patients with PAP has not been reported. Here, we describe such treatment of a patient via avelumab plus axitinib therapy. After four courses of treatment, computed tomography showed size reduction of the pulmonary metastatic nodule and improvement of PAP. This study highlights that avelumab plus axitinib therapy is a safe and effective treatment option for metastatic renal cell carcinoma, even in patients with PAP. |
| Databáze: | OpenAIRE |
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