Uncommon Presentation of Granulomatosis with Polyangiitis Mimicking Metastatic Lung Cancer
| Autor: | Johanna Elversang, Karl Emil Nelveg-Kristensen, Bonnie Colville-Ebeling, Johan Löfgren, E. Urbanska, Wladimir Szpirt |
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| Rok vydání: | 2021 |
| Předmět: |
Medicine (General)
medicine.medical_specialty Pleural effusion 030232 urology & nephrology Case Report vasculitis 03 medical and health sciences R5-920 0302 clinical medicine Biopsy medicine Lung cancer intrathoracic lesions Lymph node 030203 arthritis & rheumatology granulomatosis with polyangiitis medicine.diagnostic_test business.industry General Medicine GPA medicine.disease medicine.anatomical_structure Radiology Granulomatosis with polyangiitis Vasculitis business Pulmonary Mass lung cancer differential diagnosis Systemic vasculitis |
| Zdroj: | Clinics and Practice, Vol 11, Iss 42, Pp 293-302 (2021) Clinics and Practice |
| ISSN: | 2039-7283 |
| DOI: | 10.3390/clinpract11020042 |
| Popis: | Diagnosis of anomalous intrathoracic lesions may be challenging and require a multidisciplinary approach. We present a case of granulomatosis with polyangiitis (GPA) clinically and radiologically mimicking metastatic lung cancer with a bilateral pulmonary mass, mediastinal and cervical lymph node involvement, and pleural effusion. Surgical biopsy of the thoracic lesion revealed necrotic granulomatous inflammation, and the final diagnosis was subsequently confirmed by kidney biopsy and biochemical parameters. This case illustrates how comprehensive diagnosis secures timely and relevant treatment. Systemic vasculitis may be one of the key differential diagnoses in patients with multiorgan involvement, especially with pattern-mimicking lung cancer. |
| Databáze: | OpenAIRE |
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