Neonatal rodent ventilation and clinical correlation in congenital diaphragmatic hernia

Autor: Vikas S. Gupta, Cory Wilson, Elizabeth C. Popp, Siqin Zhaorigetu, Scott Collum, Di Jin, Amir M. Khan, Harry Karmouty‐Quintana, Kevin P. Lally, Matthew T. Harting
Rok vydání: 2022
Předmět:
Zdroj: Pediatric pulmonologyREFERENCES. 57(7)
ISSN: 1099-0496
Popis: Ventilator management is a critical part of managing congenital diaphragmatic hernia (CDH). We aimed to use a murine model and patient data to study CDH-associated differences in oxygenation, airway resistance, and pulmonary mechanics by disease severity.We used the nitrofen model of CDH. For control and CDH rodents, data were collected within the first hour of life. Oxygen saturations (SpOControl rodents had a median SpONewborns with CDH have lower SpO
Databáze: OpenAIRE