Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA

Autor: Pamela S. O’Brien, Ellen N. Kersh, John R. Papp, Alan Y Komeya, David L. Trees, A. Jeanine Abrams, Alan R. Katz, Robert D. Kirkcaldy, Gail Y. Kunimoto, Juval E Tomas, Olusegun O. Soge, Derek H. Harauchi, A. Christian Whelen, Norman P. O’Connor, Glenn M Wasserman, Eloisa V. Maningas, Evelyn E. Nash
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
Sexually transmitted disease
Sexually Transmitted Diseases
Bacterial
sexual transmitted infections
Epidemiology
Gonorrhea
lcsh:Medicine
Azithromycin
medicine.disease_cause
phylogenic cluster
0302 clinical medicine
030212 general & internal medicine
Clade
bacteria
Phylogeny
antimicrobial drug resistance
Ceftriaxone
Dispatch
sexually transmitted disease
Anti-Bacterial Agents
Infectious Diseases
Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae
Hawaii
medicine.drug
Microbiology (medical)
030106 microbiology
Microbial Sensitivity Tests
Biology
Hawaii
Microbiology
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Antibiotic resistance
Drug Resistance
Bacterial
medicine
Humans
lcsh:RC109-216
antimicrobial resistance
in vitro susceptibility
lcsh:R
bacterial infection
medicine.disease
Virology
Neisseria gonorrhoeae
United States
genomic analysis
Multilocus sequence typing
STI
STD
Genome
Bacterial
Multilocus Sequence Typing
Zdroj: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 23, Iss 5, Pp 830-832 (2017)
ISSN: 1080-6059
1080-6040
Popis: During 2016, eight Neisseria gonorrhoeae isolates from 7 patients in Hawaii were resistant to azithromycin; 5 had decreased in vitro susceptibility to ceftriaxone. Genomic analysis demonstrated a distinct phylogenetic clade when compared with local contemporary strains. Continued evolution and widespread transmission of these strains might challenge the effectiveness of current therapeutic options.
Databáze: OpenAIRE
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