Asymmetric Deep Stromal Keratopathy in a Patient With Multiple Myeloma
| Autor: | Seth W. Meskin, Jessica Chow, John H. Sinard, Natalia Neparidze, Patrick A. Coady, Ron A. Adelman, Laurel T. Tainsh |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Pathology
medicine.medical_specialty Stromal cell Visual acuity Corneal Stroma Paraproteinemias Visual Acuity Lesion 03 medical and health sciences Immunoglobulin kappa-Chains 0302 clinical medicine Corneal Opacity Stroma Medicine Humans 030212 general & internal medicine Multiple myeloma Aged 80 and over Unusual case business.industry medicine.disease Ophthalmology Monoclonal gammopathy 030221 ophthalmology & optometry Histopathology Female medicine.symptom business Multiple Myeloma Keratoplasty Penetrating |
| Zdroj: | Cornea. 36(3) |
| ISSN: | 1536-4798 |
| Popis: | Purpose To report a case of asymmetric deep stromal keratopathy in a patient with multiple myeloma. Methods Case report and literature review. Results An 85-year-old woman was found to have progressive visually significant left-sided deep stromal opacity in the setting of monoclonal gammopathy. Hematologic workup resulted in a diagnosis of IgG kappa multiple myeloma. Histopathology was significant for semicrystalline deposits in the posterior stroma. The patient's visual acuity improved to 20/50 7 months after penetrating keratoplasty. A similar deep stromal lesion appeared in the right eye 2 years after initial presentation. Conclusions We present an unusual case of paraproteinemic keratopathy with a uniquely asymmetric presentation that resulted in a diagnosis of multiple myeloma. |
| Databáze: | OpenAIRE |
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