Small RNAs and RNAi pathways in meiotic prophase I

Autor:	Rebecca J. Holmes, Paula E. Cohen
Rok vydání:	2007
Předmět:	Male Heterochromatin Centromere Biology Gametogenesis Meiotic Prophase I Meiosis RNA interference Schizosaccharomyces Genetics Animals Humans Gene Silencing Mammals Models Genetic fungi Yeast Cell biology RNA Female RNA Interference Chromatoid body
Zdroj:	Chromosome Research. 15:653-665
ISSN:	1573-6849 0967-3849
DOI:	10.1007/s10577-007-1144-z
Popis:	RNA interference is involved in many aspects of cell biology, and the recent identification of germ-cell specific small RNAs has led to speculation that RNAi might also be involved in gametogenesis. Work in yeast indicates that RNAi is involved in establishing and maintaining heterochromatin at centromeres, an important component of yeast and mammalian meiosis. Here we review developments in the field of RNAi and relate these to possible roles in mammalian gametogenesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75157a4326b159d9a0cf1df5fbead5eb https://doi.org/10.1007/s10577-007-1144-z Zobrazit plný text záznamu Full text from SpringerLink