Gas chromatographic—mass spectrometric detection of circulating plasticizers in surgical patients
| Autor: | Gulab Jham, Thomas F. Nealon, Andre L. C. Smit, Robert G. Hicks, Nathaniel P. H. Ching, Challa Subbarayan, David V. Bowen, C. Grossi, Frank H. Field |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
endocrine system
Chromatography Critical Care Critically ill Dibutyl phthalate Plasticizer Phthalate Transfusion Reaction General Chemistry Contamination Mass spectrometric Dibutyl Phthalate Gas Chromatography-Mass Spectrometry chemistry.chemical_compound chemistry Plasticizers Diethylhexyl Phthalate Environmental chemistry Humans Surgical patients |
| Zdroj: | Journal of Chromatography B: Biomedical Sciences and Applications. 222:171-177 |
| ISSN: | 0378-4347 |
| DOI: | 10.1016/s0378-4347(00)81050-6 |
| Popis: | Gas chromatographic and gas chromatographic—mass specrometric analytical techniques were employed to quantitate and confirm levels of circulating organic plasticizers in critically ill surgical patients. Two plasticizers, dibutyl phthalate (DBP) and di-(2-ethylhexyl) phthalate (DEHP), have been identified. DEHP can be found in many plastic medical devices. The DEHP levels were significant soon after transfusion or in the presence of renal dysfunction. The source of DBP is not clear at present and requires further study. The prevention of this contamination and the toxicity of these plasticizers should be investigated to ensure the safe use of plastic medical devices. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|