Differences in insulin dosing in women with type 1 diabetes before and after the menopause

Autor: Andreas Hungele, Sabine E. Hofer, Erna Kamml, Gabriele Götz, Martin Pfeifer, Irina Zürrer, Reinhard W. Holl, Ingrid Schütz-Fuhrmann, Florian Kopp, Andreas Melmer
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Popis: The menstrual cycle increases insulin requirements in a subset of women with type 1 diabetes as a result of reduced insulin action through sexual hormones. If exposure to sexual hormones declines during the menopause, adaptions of insulin dosing may be required. However, there are no validated recommendations available on how to adapt insulin treatment in postmenopausal women with type 1 diabetes. The present study compared insulin dosing profiles of 630 premenopausal and 548 postmenopausal women, who had long-term type 1 diabetes and used continuous subcutaneous insulin infusion. Data were extracted from the German "Diabetes-Patienten- Verlaufsdokumentation". It was found that total daily insulin (p
Databáze: OpenAIRE