Differences in insulin dosing in women with type 1 diabetes before and after the menopause
Autor: | Andreas Hungele, Sabine E. Hofer, Erna Kamml, Gabriele Götz, Martin Pfeifer, Irina Zürrer, Reinhard W. Holl, Ingrid Schütz-Fuhrmann, Florian Kopp, Andreas Melmer |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
media_common.quotation_subject medicine.medical_treatment Renal function Internal medicine Diabetes mellitus medicine Humans Hypoglycemic Agents Insulin ddc:610 Menstrual cycle media_common Glycated Hemoglobin Type 1 diabetes business.industry Incidence (epidemiology) General Medicine medicine.disease Menopause Diabetes Mellitus Type 1 Endocrinology Female business Body mass index |
Popis: | The menstrual cycle increases insulin requirements in a subset of women with type 1 diabetes as a result of reduced insulin action through sexual hormones. If exposure to sexual hormones declines during the menopause, adaptions of insulin dosing may be required. However, there are no validated recommendations available on how to adapt insulin treatment in postmenopausal women with type 1 diabetes. The present study compared insulin dosing profiles of 630 premenopausal and 548 postmenopausal women, who had long-term type 1 diabetes and used continuous subcutaneous insulin infusion. Data were extracted from the German "Diabetes-Patienten- Verlaufsdokumentation". It was found that total daily insulin (p |
Databáze: | OpenAIRE |
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