Constituents from the Stems ofGoniothalamus griffithii
| Autor: | Chao Ming Li, Li Guang Lou, Qing Mu, Ruo Yan Liu, Chang Qi Hu, Han-Dong Sun, Wei Dong Tang |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Aporphines
Magnetic Resonance Spectroscopy Stereochemistry Annonaceae Pharmaceutical Science Pharmacognosy Peptides Cyclic Analytical Chemistry Inhibitory Concentration 50 chemistry.chemical_compound Cell Line Tumor Drug Discovery Humans Aporphine Pharmacology chemistry.chemical_classification Plant Stems biology Plant Extracts Alkaloid Organic Chemistry biology.organism_classification Antineoplastic Agents Phytogenic Enol Cyclic peptide Complementary and alternative medicine chemistry Molecular Medicine Goniothalamus griffithii Phytotherapy |
| Zdroj: | Planta Medica. 69:826-830 |
| ISSN: | 1439-0221 0032-0943 |
| DOI: | 10.1055/s-2003-43219 |
| Popis: | A new cyclopeptide, grifficyclocin A (1), and a new aporphine alkaloid, griffinin (2) were isolated together with two known styryllactones from the stems of Goniothalamus griffithii. Their structures were identified spectroscopically and chemically. Among them, the griffinin (2) was isolated as the enol form in two tautomers, and the two known styryllactones, goniothalamin (3) and 8- O-acetylgoniotriol (4), showed selective in vitro antitumor activities. |
| Databáze: | OpenAIRE |
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