Effects of grape juice consumption on oxidative stress and inflammation in male volleyball players: A randomized, double-blind, placebo-controlled clinical trial
| Autor: | Jéssica Pereira Marinho, Eduardo Peil Marques, Amanda Stolzenberg Blembeel, Alessandra Peres, Mirian Salvador, Daniela Pochmann, Jerri Luiz Ribeiro, Viviane Rostirola Elsner, Maria Júlia Vieira da Cunha Goulart, Nicolli Cariello Martins, Gilson Pires Dorneles, Gabriella Berwig Möller, Caroline Dani, Isabel Cristina Teixeira Proença |
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| Rok vydání: | 2020 |
| Předmět: |
Complementary and Manual Therapy
Male Antioxidant Adolescent medicine.medical_treatment Physical exercise Pharmacology Athletic Performance Placebo Protein oxidation medicine.disease_cause Lipid peroxidation Histones 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Double-Blind Method medicine Humans Vitis 030212 general & internal medicine Muscle Strength Creatine Kinase Advanced and Specialized Nursing Inflammation biology business.industry food and beverages Fruit and Vegetable Juices Purple Grape Juice Oxidative Stress Volleyball Complementary and alternative medicine chemistry biology.protein Creatine kinase business 030217 neurology & neurosurgery Oxidative stress |
| Zdroj: | Complementary therapies in medicine. 54 |
| ISSN: | 1873-6963 |
| Popis: | Introduction Some foods are also demonstrated benefits, such as anti-inflammatory, antioxidant, and ergogenic activity, similar to that of sports supplements. Grape juice has been considered an important source of polyphenols and these compounds could promote positive effects to the sports players. In this sense, the objective was to evaluate the effects of purple grape juice consumption on indicators of oxidative stress, inflammation, muscle damage, global histone H4 acetylation levels, and muscle strength and muscle power in volleyball athletes. Methods This is a randomized double-blind clinical trial in which 12 male volleyball players (16 ± 0.6 years old) participated in three different moments with match simulation: control (without beverage) (WB), grape juice (GJ) and placebo (PLA) (400 mL/day of grape juice or placebo (maltodextrin) for 14 days in a cross-over model). Before and immediately after each match, blood collection for analysis of indicators of systemic redox status, systemic concentrations of Interferon-γ (IFN- γ) and Interleukin-4 (IL-4), muscle damage, by Creatine Kinase (CK-NAC) and levels of global histone H4 acetylation were performed, as well as handgrip strength (HG) and lower limb power tests. Results Consumption of grape juice significantly reduced lipid peroxidation (p = 0.04) and Deoxyribonucleic Acid (DNA) damage (p = 0.01) after the match. IFN-γ levels, IL-4, CK-NAC, and histone H4 acetylation post-match did not alter with the grape juice consumption. Lower limb power improved after acute exercise in WB and GJ conditions (p Conclusion In this pilot trial, the intake of grape juice for two weeks seems to reduce the protein oxidation and DNA damage by intermittent physical exercise, without epigenetics influence. |
| Databáze: | OpenAIRE |
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