Platelet-Rich Plasma for Arthroscopic Repair of Large to Massive Rotator Cuff Tears
| Autor: | Kang Sup Yoon, Seung-yeon Lee, Young Gil Lee, Sue Shin, Chris Hyunchul Jo, Won Hyoung Shin, Ji Sun Shin, Hyang Sun Kim |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Physical Therapy Sports Therapy and Rehabilitation Arthroplasty Rotator Cuff Injuries law.invention Arthroscopy Rotator Cuff Randomized controlled trial Recurrence Shoulder Pain law medicine Humans Orthopedics and Sports Medicine Rotator cuff Muscle Strength Range of Motion Articular Aged medicine.diagnostic_test Platelet-Rich Plasma business.industry Rotator cuff injury Magnetic resonance imaging Middle Aged medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Platelet-rich plasma Tears Female business |
| Zdroj: | The American Journal of Sports Medicine. 41:2240-2248 |
| ISSN: | 1552-3365 0363-5465 |
| DOI: | 10.1177/0363546513497925 |
| Popis: | Platelet-rich plasma (PRP) is expected to have a biological augmentation potential in the healing of various diseases and injuries, including rotator cuff tears. However, few evaluations have been performed specifically for large to massive tears.To assess the efficacy of PRP augmentation in patients undergoing arthroscopic repair for large to massive rotator cuff tears.Randomized controlled trial; Level of evidence, 1.A total of 48 patients scheduled for arthroscopic repair of large to massive rotator cuff tears were randomly assigned to receive either PRP-augmented (PRP group) or conventional treatment (conventional group). In the PRP group, 3 PRP gels (3 × 3 mL) were applied to each patient between the torn end and the greater tuberosity. The primary outcome measure was the retear rate assessed by magnetic resonance imaging (MRI) or computed tomographic arthrography (CTA) at a minimum of 9 months after surgery. Secondary outcome measures included pain, range of motion, muscle strength, overall satisfaction, functional scores, and the change in cross-sectional area (CSA) of the supraspinatus.The retear rate of the PRP group (20.0%) was significantly lower than that of the conventional group (55.6%) (P = .023). Clinical outcomes showed no statistical difference between the 2 groups (all P.05) except for the overall function (P = .043). The change in 1-year postoperative and immediately postoperative CSA was significantly different between the 2 groups: -15.54 ± 94.34 mm² in the PRP group versus -85.62 ± 103.57 mm² in the conventional group (P = .047).The application of PRP for large to massive rotator cuff repairs significantly improved structural outcomes, as evidenced by a decreased retear rate and increased CSA of the supraspinatus compared with repairs without PRP augmentation. While there was no significant difference in clinical outcomes except the overall shoulder function after 1-year follow-up, better structural outcomes in the PRP group might suggest improved clinical outcomes at longer term follow-up. |
| Databáze: | OpenAIRE |
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