Post-Lyme disease syndrome
| Autor: | Joanna Ścieszka, Józefa Dąbek, Paweł Cieślik |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Musculoskeletal pain
medicine.medical_specialty biology business.industry Immunology Disease medicine.disease biology.organism_classification xenodiagnosis Lyme disease Rheumatology post-Lyme disease syndrome Borrelia burgdorferi medicine Immunology and Allergy In patient Original Article Intensive care medicine business Xenodiagnosis |
| Zdroj: | Reumatologia |
| ISSN: | 0034-6233 |
| Popis: | About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. These two terms are used interchangeably. The pathogenesis of PLDS has been controversial. The hypothesis that patients with PLDS may harbor hidden reservoirs of Borrelia burgdorferi after their initial antibiotic treatment is difficult to accept. The prospective, double-blind studies contradict this point of view. Also, recently published research applying xenodiagnosis to PLDS supports the opinion that PLDS most likely has an autoimmune background. Lengthy courses of antibiotics are not justified in patients with PLDS because of the lack of benefit, and they are fraught with hazards. Most patients with PLDS recover from persistent symptoms with time. However, it can take months before they feel completely well. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|