Impact of Triple-Negative Breast Cancer Phenotype on Prognosis in Patients with Stage I Breast Cancer
| Autor: | Jeong Eun Kim, Heui June Ahn, Byung Ho Son, Sei Hyun Ahn, Jin-Hee Ahn, Dok Hyun Yoon, Kyung Hae Jung, Gyung Yub Gong, Sung-Bae Kim, Mi-Jung Kim |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Multivariate analysis Population HER2/neu Breast cancer Internal medicine Medicine In patient education Triple-negative breast cancer education.field_of_study biology business.industry medicine.disease Prognosis Phenotype Surgery biology.protein Original Article Breast neoplasms business Stage I breast cancer |
| Zdroj: | Journal of Breast Cancer |
| ISSN: | 2092-9900 1738-6756 |
| Popis: | Purpose Although most patients with stage I breast cancer have a good prognosis, their clinical outcomes may vary significantly. We assessed clinical outcomes and prognostic factors in stage I breast cancer patients with and without triple-negative breast cancer (TNBC) phenotype. Methods Of 2,489 patients undergoing breast cancer surgery between January 1998 and December 2002, 554 (22.3%) had stage I breast cancer (tumor size ≤2 cm, and lymph node-negative). TNBC was defined as a primary tumor negative for estrogen and progesterone receptors (Allred scores 1 cm (87.2% vs. 75.8%, p=0.028) and received adjuvant chemotherapy (79.5% vs. 44.7%, p |
| Databáze: | OpenAIRE |
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