Consensus of the Spanish society of laboratory medicine and the Spanish society of medical oncology on the methodology and criteria for evaluation of circulating tumour markers in breast cancer
Autor: | T. Quintanar-Verdúguez, E. Galve-Calvo, F. Ayala de la Peña, J. M. Augé-Fradera, S. de la Cruz, B. Ortiz-Muñoz, J. Trapé-Pujol, Jose D Santotoribio, J. García-Gómez, Á. González-Hernández |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
0301 basic medicine
Oncology p53 Cancer Research medicine.medical_specialty Medical laboratory Breast Neoplasms Disease Special Article 03 medical and health sciences 0302 clinical medicine Breast cancer Internal medicine Biomarkers Tumor Medicine Humans Hematologic Tests business.industry Tumor suppressor General Medicine medicine.disease 030104 developmental biology 030220 oncology & carcinogenesis Carcinoembryonic antigen Female business Biomarkers |
Zdroj: | Dadun. Depósito Académico Digital de la Universidad de Navarra instname Clinical & Translational Oncology CLINICAL & TRANSLATIONAL ONCOLOGY r-FISABIO. Repositorio Institucional de Producción Científica |
ISSN: | 1699-048X |
DOI: | 10.1007/s12094-020-02529-x.pdf |
Popis: | The measurement of circulating tumour markers (TMs) for the diagnosis or monitoring of breast cancer has sometimes been considered of limited utility. In addition to the overinterpretation of irrelevant changes in marker levels, the characteristics of the patient, the disease or other pathologies that can modify them are often not considered in their evaluation. On the other hand, there are recent data on the relationship of TMs with molecular subtypes and on their prognostic value, the knowledge of which may improve their clinical utility. This consensus article arises from a collaboration between the Spanish Society of Laboratory Medicine (SEQCML) and the Spanish Society of Medical Oncology (SEOM). It aims to improve the use and interpretation of circulating TMs in breast cancer. The text summarizes the current knowledge and available evidence on the subject and proposes a series of recommendations mainly focussed on the indication, the frequency of testing and the factors that should be considered for correctly interpreting changes in the levels of TMs. |
Databáze: | OpenAIRE |
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