Migraine with aura and recurrent vertigo attacks in a patient with hereditary hemorrhagic telangiectasia
| Autor: | Yasumasa Ohyagi, Koji Tanaka, Tomo Iura, Hikaru Doi, Takahisa Tateishi, Jun Ichi Kira, Tomomi Yonekawa |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Migraine Disorders Fistula medicine.medical_treatment Population Physical examination Recurrence Internal medicine Vertigo otorhinolaryngologic diseases medicine Humans Embolization education Telangiectasia education.field_of_study medicine.diagnostic_test biology business.industry medicine.disease biology.organism_classification Migraine with aura Migraine Cardiology Female Telangiectasia Hereditary Hemorrhagic Neurology (clinical) medicine.symptom business |
| Zdroj: | Rinsho Shinkeigaku. 52:499-502 |
| ISSN: | 1882-0654 0009-918X |
| DOI: | 10.5692/clinicalneurol.52.499 |
| Popis: | Hereditary hemorrhagic telangiectasia (HHT) is characterized by systemic vascular diseases mainly shown as arterio-visnous fistula (AVF). Here, we presented a 29-year-old woman with HHT complicated with migraine with aura (MWA) and vertigo. At the age of twelve years, she developed migraine with visual aura. At that time, migraine attacks were seen three times a year. At the age of 29 years, she also developed speech disturbance as migraine aura. At the ages of 20 and 29 years, she repeatedly suffered from positional vertigo attacks for a month. Physical examination revealed dilation of the capillary vessels at tongue, soft palate, and nasal mucosa and AVFs were located in the upper cervical cord, parietal lobe, and bilateral lungs. These clinical findings were consistent with the diagnostic criteria of HHT. Embolization of pulmonary AVF decreased the frequency of migraine attacks during 2-year follow-up after the embolization. The frequency of migraine in patients with HHT is higher than that of general population as well as the prevalence of vertigo. Therefore, MWA and vertigo presented in the patient with HHT suggests that there is a common pathological mechanism of dysfunction of endothelial cells and R-L shunt, among HHT, MWA, and vertigo. |
| Databáze: | OpenAIRE |
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