Effectiveness of turmeric-enriched pellets to improve the immunity of Clarias batrachus toward motile Aeromonas septicemia disease
| Autor: | Isma Mulyani, Yusni Ikhwan Siregar, Morina Riauwaty |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Veterinary medicine Pellets Positive control 010501 environmental sciences Clarias 01 natural sciences General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Immunity Internal medicine medicine General Pharmacology Toxicology and Pharmaceutics 0105 earth and related environmental sciences Hematology biology General Immunology and Microbiology 04 agricultural and veterinary sciences General Medicine biology.organism_classification Aeromonas hydrophila 030104 developmental biology Aeromonas 040102 fisheries 0401 agriculture forestry and fisheries Catfish |
| Zdroj: | F1000Research. 10:169 |
| ISSN: | 2046-1402 |
| DOI: | 10.12688/f1000research.28260.1 |
| Popis: | Background: Turmeric is known as a natural remedy to improve the immunity of organisms. This study aims to understand the effectiveness of turmeric-enriched pellets to improve the immunity of Clarias batrachus to Aeromonas hydrophila. Methods: The study was conducted from May to August 2020. C. batrachus fingerlings, 7-8 cm total length (TL) and 4-5 g (BW) at baseline, were kept in 30 L aquaria (10 fishes/aquarium; three replicated/treatment). Commercial pellets were mixed with turmeric powder. There were five treatment groups: P0 (control, no turmeric); P1 (0.5 g turmeric per Kg of pellets); P2 (0.7 g/Kg); P3 (0.9 g/Kg); Pp (positive control). Thirty days after being feed with turmeric-enriched pellets, all groups of fish were infected with 0.1 ml (108) of A. hydrophila suspension, intramuscularly. The P0 group did not receive injection, while Pp group were not fed with turmeric-enriched pellets but were infected with the bacteria. Fourteen days after infection, clinical signs and hematology of the fish were studied. Results: Pp fish showed heavy clinical signs of A. hydrophila, such as loss of balance, pigmentation, hemorrhages and ulcers. P0 fish did not show any symptoms, while the treated fish reveled some clinical signs of A. hydrophila to a lesser extent than Pp, indicating that the fish is able to face the A. hydrophila attack. Hematology for Pp fish revealed high white blood cells, indicating that the fish were infected. The blood condition of the P0 fish, as well as those of the turmeric-treated fish were normal. In general, the P3 fish showed the least clinical signs of A. hydrophila and normal blood condition, indicating that P3 treatment is best. Conclusion: The best turmeric dosage to improve the immunity of C. batrachus toward A. hydrophila infection is 0.9 g/Kg pellets. |
| Databáze: | OpenAIRE |
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