Effect of the coronavirus pandemic on tumor markers
| Autor: | Burak Giray, Esra Gurbuz, Yunus Emre Purut |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Turkey
Neutrophils medicine.disease_cause Gastroenterology Procalcitonin law.invention chemistry.chemical_compound 0302 clinical medicine law Lymphocytes 030212 general & internal medicine Respiratory system Research Articles Coronavirus Aged 80 and over Leukopenia medicine.diagnostic_test Middle Aged Intensive care unit Troponin C-Reactive Protein Infectious Diseases tumor markers Female 030211 gastroenterology & hepatology alpha-Fetoproteins medicine.symptom Research Article Adult medicine.medical_specialty CA-19-9 Antigen Fibrin Fibrinogen Degradation Products coronavirus disease‐2019 03 medical and health sciences Virology Internal medicine Biomarkers Tumor medicine Humans Pandemics Aged Retrospective Studies Creatinine SARS-CoV-2 business.industry Mucin-1 COVID-19 Retrospective cohort study Carcinoembryonic Antigen chemistry CA-125 Antigen Ferritins business Liver function tests laboratory |
| Zdroj: | Journal of Medical Virology |
| ISSN: | 1096-9071 0146-6615 |
| DOI: | 10.1002/jmv.27057 |
| Popis: | The new type of coronavirus could cause severe acute respiratory syndrome and injuries in other systems as well. Multiple organ damage can occur rapidly in patients infected with coronavirus disease 2019 (COVID‐19). Previous studies have shown that many laboratory biomarkers were not within the normal ranges in COVID‐19 patients. We aimed to summarize laboratory parameters and the tumor markers in COVID‐19 patients. This is a retrospective cohort study conducted on 53 women between the ages of 19–85 years infected with COVID‐19 at a training and research hospital between May 2020 and August 2020. Of the 53 women, 16 (30.2%) had leukopenia. The mean C‐reactive protein level was 18.42 ± 59.33 mg/L. The mean procalcitonin level was 0.1 ± 0.21 µg/L. The liver function tests were within normal limits. The mean creatinine level was 0.58 ± 0.37 mg/dl. Elevated levels of α‐fetoprotein (AFP) in 1 patient, elevated levels of carcinoembryonic antigen (CEA) in 2 patients, elevated levels of cancer antigen 125 (CA125) in 4 patients, elevated levels of CA19‐9 in 2 patients, and elevated levels of CA15‐3 in 2 patients were detected. One of 4 patients who were taken to the intensive care unit had elevated levels of AFP. In addition, 2 of 4 patients who were taken to the intensive care unit had elevated levels of CA125 and CA15‐3. Except for AFP, levels of all tumor markers of the patient who died were high. We found that COVID‐19 had no effect on tumor markers (CA125, CA19‐9, CA15‐3, AFP, and CEA). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text