Experimental Design Step by Step: A Practical Guide for Beginners
Autor: | Francisco Ardini, Barbara Benedetti, Vicky Caponigro |
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Rok vydání: | 2020 |
Předmět: |
Point (typography)
business.industry Computer science Computation Design of experiments 010401 analytical chemistry 02 engineering and technology Plan (drawing) 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Analytical Chemistry response surface methodology tutorial Software Research Design optimization screening designs 0210 nano-technology Software engineering business |
Zdroj: | Critical Reviews in Analytical Chemistry. 52:1015-1028 |
ISSN: | 1547-6510 1040-8347 |
DOI: | 10.1080/10408347.2020.1848517 |
Popis: | Inside the world of chemometrics, a fundamental role is played by the experimental design. Although introduced almost a century ago (1935), it is still not widely employed by chemists and its usefulness continues to be underestimated. When asking why, the answers are often the following: it is too difficult to apply and too much experimental effort is required. Actually, a deeper knowledge on the topic could offer a different point of view. The aim of the present tutorial is to introduce the experimental design to beginners, by providing the theoretical basic principles as well as a practical guide to use the most common designs, from the experimental plan to the final optimization. Response surface methodology will be discussed, and the main terms related to model computation and statistical evaluations usually performed by software will be explained, in order to give suitable tools to properly use them. |
Databáze: | OpenAIRE |
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