Evaluation of a monoclonal antibody for detection ofHelicobacter pylori in a direct immunofluorescence test
| Autor: | U. Rodewig, Mamoun Elsheikh, B. Soudah, W. Bär, M. Varrentrapp, D. Bitter-Suermann, W. Bemb, S. Wagner, E. Glenn-Calvo, S. Fritsch |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Lipopolysaccharides Male Microbiology (medical) Pathology medicine.medical_specialty Adolescent medicine.drug_class Spirillaceae Fluorescent Antibody Technique Immunofluorescence Monoclonal antibody Sensitivity and Specificity Mice Biopsy medicine Animals Humans Direct fluorescent antibody Aged Aged 80 and over Mice Inbred BALB C Helicobacter pylori medicine.diagnostic_test biology Antibodies Monoclonal General Medicine Middle Aged biology.organism_classification In vitro Infectious Diseases Tissue sections Evaluation Studies as Topic Female Digestive System |
| Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 11:737-739 |
| ISSN: | 1435-4373 0934-9723 |
| Popis: | A monoclonal antibody was developed for detection of Helicobacter pylori in gastric tissue sections in a direct immunofluorescence test. On a comparison of the immunofluorescence test with standard methods for detection of Helicobacter pylori, i.e. culture, the urease activity test and histological examination of tissue sections, using 158 biopsy specimens, 30 specimens were positive in all methods and 64 negative. In the remaining cases comparison was not possible because either immunofluorescence (29 specimens) or the standard methods (16 specimens) gave ambiguous results. The direct immunofluorescence test may have potential as an alternative to standard methods, but further testing in a defined patient population is necessary. |
| Databáze: | OpenAIRE |
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