Additional file 1 of Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling

Autor: Zhao, Na, Gui, Xiao, Fang, Qian, Zhang, Rui, Zhu, Weiye, Zhang, Haorui, Li, Qing, Zhou, Yukun, Zhao, Jiawei, Cui, Xiao, Gao, Guangping, Tang, Huipeng, Shen, Ni, Chen, Taoyong, Song, Hongyuan, Shen, Wei
Rok vydání: 2022
Předmět:
DOI: 10.6084/m9.figshare.19501201
Popis: Additional file 1: Figure S1. The effect of GQDs on cell viability. (A) CCK-8 assay was used to evaluate cell viability after treatment with GQDs. (B)live/dead assay was used to evaluate the toxicity of GQDs in vitro. results. Viable cells were stained in green and dead cells were stained in red with Calcein- AM/PI double dyeing kit. (C) The statistical results of live/dead assay. All data was acquired by means of ± SE from at least three independent experiments, n = 3 (**P < 0.01, ****P < 0.0001). Figure S2. The effect of GQDs on the morphology of retina. These was no significant changes in the morphology of retina in both groups. Figure S3. Representative confocal images of normal mouse retinas and OIR model retinas. Periostin was highly expression in the pathological blood vessel tissue. Retinas were stained with DAPI (blue), IB4 (green) and periostin(red).
Databáze: OpenAIRE