Successful treatment of hypervirulent Klebsiella pneumoniae bacteremia with combination carbapenem and rifampicin
| Autor: | Na Li, Cai-Peng Xie, Yong-Fang Zhang, Xi Cao, Yun-Chao Mo, Hua-Ling Chen, Yong-Chun Lin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Carbapenem Combination therapy Klebsiella pneumoniae Bacteremia Infectious and parasitic diseases RC109-216 Meropenem RFP Rifampicin Article GLU glucose in the blood Internal medicine medicine KPLA Klebsiella pneumoniae liver abscess Rifampicin biology business.industry Hypervirulent Klebsiella pneumoniae Hs-CRP hypersensitive C-reactive protein BSIs bloodstream infections biology.organism_classification medicine.disease bacterial infections and mycoses Liver abscess magA mucus related gene A Infectious Diseases hvKP hypervirulent Klebsiella pneumoniae rmpA regulator of mucoid phenotype A Carbapenems Septic arthritis CK-MB MB isoenzyme of creatine kinase business CK creatine kinase medicine.drug |
| Zdroj: | IDCases, Vol 26, Iss, Pp e01276-(2021) IDCases |
| ISSN: | 2214-2509 |
| Popis: | Hypervirulent Klebsiella pneumoniae (hvKP) with a high mucus phenotype, can cause liver abscess and extrahepatic invasive infection. The morbidity of hvKP infections has increased recently. Here we describe a case report of septicemia caused by hvKP due to the term septic arthritis of right knee joint in a 29-year-old male. The patient was persistent fever with a peak temperature at 40.6 °C. However, based on the drug sensitivity, the treatment failed frequently. The patient did not improve clinically on susceptible monotherapy antimicrobial. Combination therapy with meropenem and rifampicin (RFP) lead to clinical improvement and discharge. |
| Databáze: | OpenAIRE |
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