HIV care outcomes among transgender persons with HIV infection in the United States, 2006–2021
| Autor: | Mary M. Mullins, Darrel H. Higa, Jeffrey S. Becasen, Joseph D. Morris, Christa L. Denard, Krishna Kiran Kota |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Immunology Human immunodeficiency virus (HIV) HIV Infections medicine.disease_cause Transgender Persons Transgender Humans Immunology and Allergy Medicine Viral suppression Health needs Acquired Immunodeficiency Syndrome business.industry virus diseases Continuity of Patient Care Care Continuum United States Infectious Diseases Meta-analysis Family medicine Female Transgender Person business Transphobia |
| Zdroj: | AIDS. 36:305-315 |
| ISSN: | 1473-5571 0269-9370 |
| DOI: | 10.1097/qad.0000000000003109 |
| Popis: | OBJECTIVES HIV prevalence is an estimated 14% among transgender women (TW) and 3% among transgender men (TM). HIV care is vital for viral suppression but is hindered by transphobia and HIV stigma. We assessed HIV care outcomes among transgender persons (TG) with HIV in the United States. DESIGN Systematic review and meta-analysis of peer-reviewed journal articles. METHODS We searched multiple electronic databases and CDC's HIV Prevention Research Synthesis database for 2006-September 2018. Eligible reports were US-based studies that included TG and reported HIV care outcomes. Random-effects models were used to calculate HIV care outcome rates. The protocol is registered with PROSPERO (CRD42018079564). RESULTS Few studies reported outcomes for TM; therefore, only TW meta-analysis results are reported. Twenty-one studies were identified having low-to-medium risk-of-bias scores. Among TW with HIV, 82% had ever received HIV care; 72% were receiving care, and 83% of those were retained in HIV care. Sixty-two percent were currently virally suppressed. Among those receiving HIV care or antiretroviral therapy (ART), 67% were virally suppressed at last test. Sixty-five percent were linked to HIV care ≤3 months after diagnosis. Seventy-one percent had ever been prescribed ART. Approximately 66% were taking ART, and 66% were ART-adherent. Only 56% were currently adherent the previous year. CONCLUSIONS HIV care outcomes for TW were not ideal, and research gaps exists for TM. High heterogeneity was observed; therefore, caution should be taken interpreting the findings. Integrating transgender-specific health needs are needed to improve outcomes of transgender persons across the HIV care continuum. |
| Databáze: | OpenAIRE |
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