Retrograde aortic perfusion by partial cardiopulmonary bypass: effect of mixing on measured arterial oxygen tension
| Autor: | Philip Drinker, Jeffrey A. Kelman, John L. Lehr, E. Lawrence Hanson, Jacques Bonnet-Eymard, Christian W. Stetz |
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| Rok vydání: | 1975 |
| Předmět: |
Aortic arch
medicine.medical_specialty Extracorporeal Circulation Pulmonary Circulation chemistry.chemical_element Femoral artery Oxygenators Oxygen Extracorporeal law.invention law medicine.artery Internal medicine medicine Cardiopulmonary bypass Ventilation-Perfusion Ratio Animals Cardiac Output Oxygenator Aorta Cardiopulmonary Bypass Sheep business.industry Surgery Respiratory Function Tests chemistry Anesthesia Cardiology business Perfusion Blood Flow Velocity |
| Zdroj: | Archives of surgery (Chicago, Ill. : 1960). 110(1) |
| ISSN: | 0004-0010 |
| Popis: | Partial venoarterial bypass with return of oxygenated blood to the femoral artery can produce mixing in the aorta of the blood from the oxygenator and left ventricular sources at flow rates of less than 50% of the total body flow. This was observed in six anesthetized sheep with normal lungs maintained on controlled ventilation on partial cardiopulmonary (venoarterial) bypass. The evidence of mixing increases with the extracorporeal flow rate, reaching the aortic arch in a majority of cases at the higher rates. Management of bypass and the interpretation of its effects depend on definite knowledge of the presence or absence of mixing. Partial bypass will raise the arterial oxygen tension (Pao 2 ) of the blood continuing to flow through the lungs. This effect is independent of mixing (Pao 2 ) and may be related either to the addition of oxygen to the blood or to an enhanced pulmonary ventilation-perfusion relationship. |
| Databáze: | OpenAIRE |
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