Sustained complete remission of steroid- and cyclophosphamide-resistant minimal-change disease with a single course of rituximab therapy
| Autor: | Khai Yang Ooi, Solomon Menahem, Jyotsna Janardan |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Oncology
medicine.medical_specialty Cyclophosphamide medicine.medical_treatment Disease Clinical Reports Steroid rituximab Refractory Rituximab therapy hemic and lymphatic diseases Internal medicine Medicine Minimal change disease steroid resistance Transplantation nephrotic syndrome business.industry minimal-change disease medicine.disease Nephrology Immunology Clinical Cases Rituximab business Nephrotic syndrome medicine.drug |
| Zdroj: | Clinical Kidney Journal |
| ISSN: | 2048-8513 2048-8505 |
| DOI: | 10.1093/ckj/sfu022 |
| Popis: | We report a case of steroid- and cyclophosphamide-resistant nephrotic syndrome secondary to minimal-change disease occurring in an otherwise healthy 19-year-old female, responding rapidly to two doses of rituximab therapy. Complete disease remission has been sustained up to last follow-up (32 months) despite CD19 recovery. Literature review suggests emerging evidence that rituximab may have a role to play in recurrent and/or refractory minimal-change disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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