Aneurysm permeability following coil embolization: packing density and coil distribution
| Autor: | Juyu Chueh, Alexei A. Bogdanov, Ajay K. Wakhloo, S Carniato, Spencer Coffin, Ajit S. Puri, Srinivasan Vedantham, Conrad Bzura, Matthew J. Gounis |
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| Rok vydání: | 2014 |
| Předmět: |
Area fraction
Models Anatomic medicine.medical_specialty Treatment outcome Intervention Coil Permeability Microsphere Aneurysm Basic Science medicine Humans Coil embolization business.industry Intracranial Aneurysm General Medicine medicine.disease Embolization Therapeutic Surgery Sphere packing Treatment Outcome Electromagnetic coil Permeability (electromagnetism) Cerebrovascular Circulation Neurology (clinical) business Biomedical engineering |
| Zdroj: | Journal of Neurointerventional Surgery |
| ISSN: | 1759-8486 |
| Popis: | Background Rates of durable aneurysm occlusion following coil embolization vary widely, and a better understanding of coil mass mechanics is desired. The goal of this study is to evaluate the impact of packing density and coil uniformity on aneurysm permeability. Methods Aneurysm models were coiled using either Guglielmi detachable coils or Target coils. The permeability was assessed by taking the ratio of microspheres passing through the coil mass to those in the working fluid. Aneurysms containing coil masses were sectioned for image analysis to determine surface area fraction and coil uniformity. Results All aneurysms were coiled to a packing density of at least 27%. Packing density, surface area fraction of the dome and neck, and uniformity of the dome were significantly correlated (p |
| Databáze: | OpenAIRE |
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