TRPP2 ion channels: The roles in various subcellular locations
Autor: | Peng-fei Tian, Meng-meng Sun, Xian-yu Hu, Juan Du, Wei He |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Biochimie. 201 |
ISSN: | 1638-6183 |
Popis: | TRPP2 (PC2, PKD2 or Polycytin-2), encoded by PKD2 gene, belongs to the nonselective cation channel TRP family. Recently, the three-dimensional structure of TRPP2 was constructed. TRPP2 mainly functions in three subcellular compartments: endoplasmic reticulum, plasma membrane and primary cilia. TRPP2 can act as a calcium-activated intracellular calcium release channel on the endoplasmic reticulum. TRPP2 also interacts with other Ca |
Databáze: | OpenAIRE |
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