TRPP2 ion channels: The roles in various subcellular locations

Autor: Peng-fei Tian, Meng-meng Sun, Xian-yu Hu, Juan Du, Wei He
Rok vydání: 2021
Předmět:
Zdroj: Biochimie. 201
ISSN: 1638-6183
Popis: TRPP2 (PC2, PKD2 or Polycytin-2), encoded by PKD2 gene, belongs to the nonselective cation channel TRP family. Recently, the three-dimensional structure of TRPP2 was constructed. TRPP2 mainly functions in three subcellular compartments: endoplasmic reticulum, plasma membrane and primary cilia. TRPP2 can act as a calcium-activated intracellular calcium release channel on the endoplasmic reticulum. TRPP2 also interacts with other Ca
Databáze: OpenAIRE