Characterization of extended-spectrum beta-lactamases and qnr plasmid-mediated quinolone resistance in German isolates of Enterobacter species
| Autor: | Anett Oesterlein, Marianne Abele-Horn, Sophia Müller, Matthias Frosch, Giuseppe Valenza |
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| Rok vydání: | 2010 |
| Předmět: |
Microbiology (medical)
medicine.drug_class medicine.medical_treatment Immunology Antibiotics Enterobacter Tigecycline Drug resistance Microbial Sensitivity Tests Biology Quinolones Microbiology beta-Lactamases Plasmid Antibiotic resistance Bacterial Proteins Germany Drug Resistance Bacterial polycyclic compounds medicine Humans Pharmacology Enterobacteriaceae Infections biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Anti-Bacterial Agents Multiple drug resistance Beta-lactamase medicine.drug Plasmids |
| Zdroj: | Microbial drug resistance (Larchmont, N.Y.). 17(1) |
| ISSN: | 1931-8448 |
| Popis: | The objective of this study was to characterize the antimicrobial resistance patterns of 100 clinical isolates of Enterobacter spp. with special regard to the occurrence of extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated quinolone resistance by qnr-determinants. The rate of ESBL- and qnr-positive isolates was 7% and 14%, respectively. Thirteen isolates harbored a qnrA1, and a further isolate harbored a qnrB4 gene. Moreover, qnr-determinants were significantly associated with ESBL-expression. No carbapeneme or tigecycline resistance was detected in the collective tested. To conclude, these data confirm the increase of multiple antimicrobial resistance mechanisms in Enterobacter spp. |
| Databáze: | OpenAIRE |
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