Acute kidney injury in paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) is not associated with progression to chronic kidney disease
| Autor: | Rukshana Shroff, Nadeesha Lakmal Mudalige, Pascale du Pré, Douglas J Stewart, Mae Johnson, Jelena Stojanovic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Nephrology
Male medicine.medical_specialty nephrology urologic and male genital diseases paediatrics chemistry.chemical_compound Risk Factors Internal medicine medicine Humans Renal Insufficiency Chronic Child Pandemics Triglycerides Original Research Univariate analysis Creatinine biology business.industry SARS-CoV-2 Incidence (epidemiology) Incidence C-reactive protein Acute kidney injury COVID-19 Acute Kidney Injury medicine.disease Respiration Artificial Systemic Inflammatory Response Syndrome United Kingdom C-Reactive Protein chemistry Pediatrics Perinatology and Child Health biology.protein Disease Progression Female Complication business Kidney disease Follow-Up Studies |
| Zdroj: | Archives of Disease in Childhood |
| ISSN: | 1468-2044 0003-9888 |
| Popis: | Background Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) is a rare complication of SARS-CoV-2 associated with single or multiorgan dysfunction. Objective We aimed to evaluate the incidence of acute kidney injury (AKI) and risk factors for kidney dysfunction in PIMS-TS, with reporting of 6-month renal follow-up data. We also evaluated renal involvement between first and second waves of the SARS-CoV-2 pandemic in the UK, the latter attributed to the Alpha variant. Design A single-centre observational study was conducted through patient chart analysis. Setting Data were collected from patients admitted to Great Ormond Street Hospital, London, UK, between April 2020 and March 2021. Patients 110 patients Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (also known as MIS-C) was first described just over one year ago. Data on morbidity and outcome are needed. Acute Kidney Injury occurred in 30% of children in this cohort, but all recovered. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|