Is gonorrhea becoming untreatable?
| Autor: | Victoria F Miari, Bambos M. Charalambous, Paula Blomquist, Jane P Biddulph |
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| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Chlamydia Cephalosporin Resistance Gonorrhea Disease Nucleic acid amplification technique Biology medicine.disease medicine.disease_cause Microbiology Neisseria gonorrhoeae Anti-Bacterial Agents Cephalosporins Antibiotic resistance Sexual behavior Epidemiology Immunology medicine Humans Treatment Failure Intensive care medicine Nucleic Acid Amplification Techniques |
| Zdroj: | Future Microbiology. 9:189-201 |
| ISSN: | 1746-0921 1746-0913 |
| Popis: | ABSTRACT: An estimated 498 million new cases of curable sexually transmitted infections occur worldwide annually. Of these, 106 million are gonococcal infections, rendering gonorrhea the second most prevalent bacterial sexually transmitted infection after chlamydia. A decline in susceptibility to extended-spectrum cephalosporins, as well as treatment failures, have been identified worldwide. This, together with the associated epidemiological and socioeconomic burden, is of increasing concern. Currently, the effectiveness of antibiotic resistance control measures is limited. Barriers include the lack of therapeutic options, the difficulties of reducing high-risk sexual behavior and Neisseria gonorrhoeae’s propensity to rapidly acquire resistance determinants. While the disease remains treatable for the moment, we need to anticipate and be prepared for the arrival and spread of untreatable gonorrhea by using a multifaceted approach and search for other, perhaps novel control strategies. |
| Databáze: | OpenAIRE |
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