Artificial rearing alters the response of rats to natural and drug-mediated rewards
| Autor: | Patricia E. Wainwright, D. McCutcheon, Linda A. Parker, Shadna A. Rana, Anna M. Lomanowska |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Narcotics Sucrose medicine.medical_specialty Social Environment Affect (psychology) Open field Developmental psychology Rats Sprague-Dawley Food Preferences Behavioral Neuroscience Reward Developmental Neuroscience Preference test Emotionality Internal medicine Conditioning Psychological Developmental and Educational Psychology medicine Animals Gastrostomy Behavior Animal Morphine Conditioned response Brain Artificial rearing Rats Affect Endocrinology Anxiety Female medicine.symptom Psychology Developmental Biology medicine.drug |
| Zdroj: | Developmental Psychobiology. 48:301-314 |
| ISSN: | 1098-2302 0012-1630 |
| DOI: | 10.1002/dev.20139 |
| Popis: | Artificial rearing (AR) of infant rats permits precise control over key features of the early environment without maternal influence. The present study examined the behavioral response of AR rats towards natural and drug-mediated rewards, as well as their exploratory and affective behaviors. Adolescent AR rats showed increased preference for sucrose consumption relative to chow and demonstrated greater activity in the open field and in the elevated plus-maze compared to maternally reared (MR) rats. With respect to measures of emotionality, AR rats showed enhanced avoidance of the open arms of the plus-maze, indicating increased anxiety, but they did not differ from MR rats in exploring the center of the open field. Adult AR rats displayed a stronger conditioned response to morphine in a place preference test. These findings support the potential of the AR model to contribute to understanding the role of early experience in the development of behavioral motivation. |
| Databáze: | OpenAIRE |
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