Effect of Normal Metabolites on the Oxygen-Hemoglobin Equilibrium
Autor: | N. V. Paniker, Ernest Beutler |
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Rok vydání: | 1970 |
Předmět: |
Erythrocytes
Chromatography Red Cell chemistry.chemical_element Oxygen–haemoglobin dissociation curve Carbohydrate metabolism Oxygen General Biochemistry Genetics and Molecular Biology Hemoglobins chemistry.chemical_compound Adenosine Triphosphate Glucose chemistry Glycerophosphates Pyridoxal Phosphate Hemoglobin Pyridoxal phosphate |
Zdroj: | Experimental Biology and Medicine. 135:389-391 |
ISSN: | 1535-3699 1535-3702 |
DOI: | 10.3181/00379727-135-35058 |
Popis: | SummaryA number of substances, most of them normal intermediates of red cell glucose metabolism, were tested for their effect on the shift in the oxygen dissociation curve produced by 2,3-diphosphoglycerate. None of the substances tested, with the exception of ATP and pyridoxal phosphate had any effect on the dissociation curve, either in the presence or absence of 2,3-DPG, ATP and pyridoxal phosphate caused a rightward displacement of the dissociation curve, but this occurred both in the presence and absence of 2,3-DPG and was considered to be simply an additive effect. |
Databáze: | OpenAIRE |
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