Gender Differences in Patients Presenting with First-Episode Psychosis in Hong Kong: A Three-Year Follow Up Study
| Autor: | Gloria H.Y. Wong, Kathy P. M. Chan, Christy L.M. Hui, May M.L. Lam, Chi Wing Law, Jennifer Y.M. Tang, Steve Tso, Wing Chung Chang, Eric Y.H. Chen, Dicky W.S. Chung, Cindy P.Y. Chiu, Se-Fong Hung |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Psychosis Adolescent Poison control Suicide Attempted Suicide prevention Internal medicine Injury prevention medicine Humans Young adult Psychiatry Psychiatric Status Rating Scales First episode Sex Characteristics General Medicine medicine.disease Psychiatry and Mental health Psychotic Disorders Schizophrenia Hong Kong Female Age of onset Psychology Follow-Up Studies |
| Zdroj: | Australian & New Zealand Journal of Psychiatry. 45:199-205 |
| ISSN: | 1440-1614 0004-8674 |
| Popis: | Objective: The aim of the current study was to investigate gender differences with respect to pre-treatment characteristics, clinical presentation, service utilization and functional outcome in patients presenting with first-episode psychosis. Methods: A total of 700 participants (men, n = 360; women, n = 340) aged 15 to 25 years consecutively enrolled in a territory-wide first-episode psychosis treatment programme in Hong Kong from July 2001 to August 2003 were studied. Baseline and three-year follow up variables were collected via systematic medical file review. Results: At service entry, men had significantly lower educational attainment (p < 0.01), longer median duration of untreated psychosis (p < 0.001), fewer past suicidal attempts (p < 0.01), more severe negative symptoms (p < 0.05) and fewer affective symptoms (p < 0.01) than women. There was no significant gender difference in age of onset. In three-year follow up, men had more prominent negative symptoms (p < 0.001), fewer affective symptoms (p < 0.01), more violent behaviour and forensic records (p < 0.01), and higher rate of substance abuse (p < 0.01). Women achieved higher levels of functioning than men (Social Occupational Functioning Assessment Scale (SOFAS), p < 0.001) and a significantly higher proportion of women than men engaged in full-time employment or study for at least 12 consecutive months (p < 0.001) in the initial three years after psychiatric treatment. Conclusion: Notable gender differences in clinical profiles, illness trajectory and functional outcome were demonstrated in Chinese young people suffering from first-episode psychosis. Differential needs between men and women and hence gender-specific therapeutic strategies should be considered in early intervention service. |
| Databáze: | OpenAIRE |
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